Top

Is stem cell therapy less effective in older patients with chronic diseases?

January 13, 2015 by · Leave a Comment 

A promising new therapeutic approach to treat a variety of diseases involves taking a patient’s own cells, turning them into stem cells, and then deriving targeted cell types such as muscle or nerve cells to return to the patient to repair damaged tissues and organs. But the clinical effectiveness of these stem cells has only been modest, which may be due to the advanced age of the patients or the effects of chronic diseases such as diabetes and cardiovascular disease, according to a probing Review article published inBioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers . The article is available on theBioResearch Open Access website.

Read more

Inner ear stem cells hold promise for restoring hearing

June 22, 2014 by · Leave a Comment 

Spiral ganglion cells are essential for hearing and their irreversible degeneration in the inner ear is common in most types of hearing loss. Adult spiral ganglion cells are not able to regenerate. However, new evidence in a mouse model shows that spiral ganglion stem cells present in the inner ear are capable of self-renewal and can be grown and induced to differentiate into mature spiral ganglion cells as well as neurons and glial cells, as described in an article inBioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

Read more

Novel marker discovered for stem cells derived from human umbilical cord blood

April 18, 2014 by · Leave a Comment 

he development of stem cell therapies to cure a variety of diseases depends on the ability to characterize stem cell populations based on cell surface markers. Researchers from the Finnish Red Cross have discovered a new marker that is highly expressed in a type of stem cells derived from human umbilical cord blood, which they describe in an article in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

Read more

Critical factor (BRG1) identified for maintaining stem cell pluripotency

February 9, 2014 by · Leave a Comment 

he ability to reprogram adult cells so they return to an undifferentiated, pluripotent state—much like an embryonic stem cell—is enabling the development of promising new cell therapies. Accelerating progress in this field will depend on identifying factors that promote pluripotency, such as the Brg1 protein described in a new study published in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

Read more

3D printing breakthrough with human embryonic stem cells

February 5, 2013 by · Leave a Comment 

A team of researchers from Scotland has used a novel 3D printing technique to arrange human embryonic stem cells (hESCs) for the very first time.

Read more

Researchers make critical leukemia stem cell discovery

December 13, 2010 by · Leave a Comment 

Researchers at King’s College London have discovered that leukaemic stem cells can be reversed to a pre-leukaemic stage by suppressing a protein called beta-catenin found in the blood.

Read more

Bottom