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Scientists sequence genome of worm that can regrow body parts, seeking stem cell insights

September 22, 2015 by · Leave a Comment 

Tourists spending a recuperative holiday on the Italian coast may be envious of the regenerative abilities of locally found flatworm Macrostomum lignano. Named for its discovery near the Italian beach town of Lignano Sabbiadoro, this tiny worm can regenerate almost its whole body following an injury, and researchers have long been trying to understand how it’s able to pull off this trick.

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Team pinpoints genes that make plant stem cells, revealing origin of beefsteak tomatoes

May 26, 2015 by · Leave a Comment 

A team of scientists at Cold Spring Harbor Laboratory (CSHL) has identified a set of genes that control stem cell production in tomato. Mutations in these genes explain the origin of mammoth beefsteak tomatoes. More important, the research suggests how breeders can fine-tune fruit size in potentially any fruit-bearing crop. The research appears online today in Nature Genetics.

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Researchers generate long-lasting blood vessels from reprogrammed human cells

July 16, 2013 by · Leave a Comment 

Massachusetts General Hospital (MGH) researchers have used vascular precursor cells derived from human induced pluripotent stem cells (iPSCs) to generate, in an animal model, functional blood vessels that lasted as long as nine months. In their report being published in PNAS Early Edition, the investigators describe using iPSCs – reprogrammed adult cells that have many of the characteristics of embryonic stem cells – from both healthy adults and from individuals with type 1 diabetes to generate blood vessels on the outer surface of the brain or under the skin of mice.

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Stem cell mobilization therapy found to be safe for bone marrow donors

August 11, 2011 by · Leave a Comment 

(WASHINGTON, August 11, 2011) – According to a study published in Blood, the Journal of the American Society of Hematology (ASH), researchers have reported that administration of granulocyte colony-stimulating factor (G-CSF), a drug that releases stem cells from the bone marrow into the blood, is unlikely to put healthy stem cell donors at risk for later development of abnormalities involving loss or gains of chromosomes that have been linked to hematologic disorders such as myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).

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