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NYSCF Global Stem Cell ArrayTM brings precision medicine one step closer to the clinic

August 3, 2015 by · Leave a Comment 

Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute successfully designed a revolutionary, high-throughput, robotic platform that automates and standardizes the process of transforming patient samples into stem cells. This unique platform, the NYSCF Global Stem Cell ArrayTM, for the first time gives researchers the scale to look at diverse populations to better understand the underlying causes of disease and create new individually tailored treatments, enabling precision medicine in patient care.

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Drugs stimulate body’s own stem cells to replace brain cells lost in multiple sclerosis

April 21, 2015 by · Leave a Comment 

A pair of topical medicines already alleviating skin conditions each may prove to have another, even more compelling use: instructing stem cells in the brain to reverse damage caused by multiple sclerosis.

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Bone stem cells shown to regenerate bones and cartilage in adult mice

January 16, 2015 by · Leave a Comment 

A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice. The discovery by researchers at Columbia University Medical Center (CUMC) is reported today in the online issue of the journal Cell.

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Identifying the source of stem cells

October 30, 2014 by · Leave a Comment 

When most animals begin life, cells immediately begin accepting assignments to become a head, tail or a vital organ. However, mammals, including humans, are special. The cells of mammalian embryos get to make a different first choice – to become the protective placenta or to commit to forming the baby.

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UT Southwestern cancer biologists link tumor suppressor gene to stem cells

March 27, 2014 by · Leave a Comment 

ust as archeologists try to decipher ancient tablets to discern their meaning, UT Southwestern Medical Center cancer biologists are working to decode the purpose of an ancient gene considered one of the most important in cancer research.

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Alzheimer’s research team employs stem cells to understand disease processes and study new treatment

March 9, 2014 by · Leave a Comment 

A team of Alzheimer’s disease (AD) researchers at Brigham and Women’s Hospital (BWH) has been able to study the underlying causes of AD and develop assays to test newer approaches to treatment by using stem cells derived from related family members with a genetic predisposition to (AD).

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New stem cells go back further

October 31, 2013 by · Leave a Comment 

One of the obstacles to employing human embryonic stem cells for medical use lies in their very promise: They are born to rapidly differentiate into other cell types. Until now, scientists have not been able to efficiently keep embryonic stem cells in their pristine stem state. The alternative that has been proposed to embryonic stem cells – reprogrammed adult cells called induced pluripotent stem cells (iPS cells) – have similar limitations. Though these can differentiate into many different cell types, they retain signs of “priming,” – commitment to specific cell lineages. A team at the Weizmann Institute of Science has now taken a large step toward removing that obstacle: They have created iPS cells that are completely “reset” to the earliest possible state and maintained them in that state. Among other things, this research may, in the future, pave the way toward the ability to grow transplant organs to order.

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Singapore scientists discover new RNA processing pathway important in human embryonic stem cells

September 11, 2013 by · Leave a Comment 

Scientists at A*STAR’s Genome Institute of Singapore (GIS), in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning of human embryonic stem cells (hESCs). This finding was reported on 8th September 2013 in the advanced online issue of the prestigious science journal Nature Cell Biology.

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Epilepsy in a dish: Stem cell research reveals clues to disease’s origins and possible treatment

July 25, 2013 by · Leave a Comment 

This diagram shows the process by which scientists can take skin cells from patients with epilepsy, convert them to stem cells, and then create neurons (brain nerve cells) from them. The induced neurons contain the same genetic mutation(s) carried by the patients. Credit: Parent lab, University of Michigan Medical School

The findings, reported by a team of scientists from the University of Michigan Medical School and colleagues, use a technique that could be called “epilepsy in a dish”.

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Salk scientists develop faster, safer method for producing stem cells

December 4, 2012 by · Leave a Comment 

A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.

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