Vital step in stem cell growth revealed

May 3, 2015 by · Leave a Comment 

Stem cells, which have the potential to turn into any kind of cell, offer the tantalizing possibility of generating new tissues for organ replacements, stroke victims and patients of many other diseases. Now, scientists at the Salk Institute have uncovered details about stem cell growth that could help improve regenerative therapies.

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In directing stem cells, study shows context matters

September 10, 2014 by · Leave a Comment 

Figuring out how blank slate stem cells decide which kind of cell they want to be when they grow up — a muscle cell, a bone cell, a neuron — has been no small task for science.

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Childhood coxsackie virus infection depletes cardiac stem cells and might compromise heart health in adults

August 2, 2014 by · Leave a Comment 

There is epidemiological evidence that links type B coxsackie virus (CVB) infection with heart disease, and research published on July 31st in PLOS Pathogens now suggests a mechanism by which early infection impairs the heart’s ability to tolerate stress at later stages of life.

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New method reveals single protein interaction key to embryonic stem cell differentiation

June 7, 2014 by · Leave a Comment 

Proteins are responsible for the vast majority of the cellular functions that shape life, but like guests at a crowded dinner party, they interact transiently and in complex networks, making it difficult to determine which specific interactions are most important.

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How a Silly Putty ingredient could advance stem cell therapies

April 14, 2014 by · Leave a Comment 

The sponginess of the environment where human embryonic stem cells are growing affects the type of specialized cells they eventually become, a University of Michigan study shows.

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Major breakthrough in stem cell manufacturing technology

March 31, 2014 by · Leave a Comment 

Scientists at The University of Nottingham have developed a new substance which could simplify the manufacture of cell therapy in the pioneering world of regenerative medicine.

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Alzheimer’s in a dish

March 6, 2014 by · Leave a Comment 

Harvard stem cell scientists have successfully converted skins cells from patients with early-onset Alzheimer’s into the types of neurons that are affected by the disease, making it possible for the first time to study this leading form of dementia in living human cells. This may also make it possible to develop therapies far more quickly and accurately than before.

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Stem cell transplant repairs damaged gut in mouse model of inflammatory bowel disease

October 18, 2013 by · Leave a Comment 

A source of gut stem cells that can repair a type of inflammatory bowel disease when transplanted into mice has been identified by researchers at the Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge and at BRIC, the University of Copenhagen, Denmark.

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Shining stem cells reveals how our skin is maintained

August 17, 2013 by · Leave a Comment 

All organs in our body rely on stem cells in order to maintain their function. The skin is our largest organ and forms a shield against the environment. New research results from BRIC, University of Copenhagen and Cambridge University, challenge current stem cell models and explains how the skin is maintained throughout life. The results have just been published in the recognized journal Cell Stem Cell.

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The surprising ability of blood stem cells to respond to emergencies

April 10, 2013 by · Leave a Comment 

A research team of Inserm, CNRS and MDC lead by Michael Sieweke of the Centre d’Immunologie de Marseille Luminy (CNRS, INSERM, Aix Marseille Université) and Max Delbrück Centre for Molecular Medicine, Berlin-Buch, today revealed an unexpected role for hematopoietic stem cells: they do not merely ensure the continuous renewal of our blood cells; in emergencies they are capable of producing white blood cells “on demand” that help the body deal with inflammation or infection. This property could be used to protect against infections in patients undergoing bone marrow transplants, while their immune system reconstitutes itself. The details of the research is published in Nature on april 10th 2013.

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