Top

A snapshot of stem cell expression

October 2, 2015 by · Leave a Comment 

Researchers on the Wellcome Genome Campus reveal new genes involved in stem cell pluripotency, new subpopulations of cells and new methods to find meaning in the data. Published in Cell Stem Cell, the findings have implications for the study of early development.

Read more

Scientists sequence genome of worm that can regrow body parts, seeking stem cell insights

September 22, 2015 by · Leave a Comment 

Tourists spending a recuperative holiday on the Italian coast may be envious of the regenerative abilities of locally found flatworm Macrostomum lignano. Named for its discovery near the Italian beach town of Lignano Sabbiadoro, this tiny worm can regenerate almost its whole body following an injury, and researchers have long been trying to understand how it’s able to pull off this trick.

Read more

Variations in cell programs control cancer and normal stem cells

September 3, 2015 by · Leave a Comment 

In the breast, cancer stem cells and normal stem cells can arise from different cell types but tap into distinct yet related stem cell programs, according to Whitehead Institute researchers. The differences between these stem cell programs may be significant enough to be exploited by future therapeutics.

Read more

Scientists grow ‘mini-lungs’ to aid the study of cystic fibrosis

March 19, 2015 by · Leave a Comment 

Scientists at the University of Cambridge have successfully created ‘mini-lungs’ using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.

Read more

Inner ear stem cells hold promise for restoring hearing

June 22, 2014 by · Leave a Comment 

Spiral ganglion cells are essential for hearing and their irreversible degeneration in the inner ear is common in most types of hearing loss. Adult spiral ganglion cells are not able to regenerate. However, new evidence in a mouse model shows that spiral ganglion stem cells present in the inner ear are capable of self-renewal and can be grown and induced to differentiate into mature spiral ganglion cells as well as neurons and glial cells, as described in an article inBioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

Read more

Seemingly invincible cancers stem cells reveal a weakness

June 7, 2014 by · Leave a Comment 

Metastatic cancer cells, which can migrate from primary tumors to seed new malignancies, have thus far been resistant to the current arsenal of anticancer drugs. Now, however, researchers at Whitehead Institute have identified a critical weakness that actually exploits one of these cells’ apparent strengths—their ability to move and invade tissues.

Read more

Functioning of aged brains and muscles in mice made younger

May 4, 2014 by · Leave a Comment 

Cambridge, MA, May 4 – Harvard Stem Cell Institute (HSCI) researchers have shown that a protein they previously demonstrated can make the failing hearts in aging mice appear more like those of young health mice, similarly improves brain and skeletal muscle function in aging mice.

Read more

Yeast, human stem cells drive discovery of new Parkinson’s disease drug targets

October 24, 2013 by · Leave a Comment 

Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson’s disease drug target and a compound capable of repairing neurons derived from Parkinson’s patients.

Read more

Stem cell transplant repairs damaged gut in mouse model of inflammatory bowel disease

October 18, 2013 by · Leave a Comment 

A source of gut stem cells that can repair a type of inflammatory bowel disease when transplanted into mice has been identified by researchers at the Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge and at BRIC, the University of Copenhagen, Denmark.

Read more

Stem cell breakthrough could set up future transplant therapies

October 11, 2013 by · Leave a Comment 

A new method for creating stem cells for the human liver and pancreas, which could enable both cell types to be grown in sufficient quantities for clinical use, has been developed by scientists.

Read more

Next Page »

Bottom