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Johns Hopkins biologist leads research shedding light on stem cells

October 8, 2015 by · Leave a Comment 

A Johns Hopkins University biologist has led a research team reporting progress in understanding the mysterious shape-shifting ways of stem cells, which have vast potential for medical research and disease treatment.

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Can stem cells cause and cure cancer?

August 13, 2015 by · Leave a Comment 

Simply put, cancer is caused by mutations to genes within a cell that lead to abnormal cell growth. Finding out what causes that genetic mutation has been the holy grail of medical science for decades. Researchers at the Texas A&M Health Science Center Institute of Biosciences and Technology believe they may have found one of the reasons why these genes mutate and it all has to do with how stem cells talk to each other.

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Stem cells that prevent birth defect also repair facial injury

April 23, 2015 by · Leave a Comment 

Researchers have pinpointed a primary cause of a rare skull disorder in infants, and the discovery could help wounded soldiers, car-wreck victims and other patients recover from disfiguring facial injuries.

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Growing functioning brain tissue in 3-D

January 30, 2015 by · Leave a Comment 

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Molecular time signalling controls stem cells during brain’s development

November 13, 2014 by · Leave a Comment 

Researchers at Karolinska Institutet in Sweden have succeeded in explaining how stem cells in the brain change to allow one type of stem cell to produce different cell types at different stages. In a study being published in the journal Neuron, researchers show that the signal molecule TGF-beta acts as a time signal that regulates the nerve stem cells’ potential at different stages of the brain’s development – knowledge that may be significant for future pharmaceutical development.

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Direct generation of neural stem cells could enable transplantation therapy

November 7, 2014 by · Leave a Comment 

Induced neural stem cells (iNSCs) created from adult cells hold promise for therapeutic transplantation, but their potential in this capacity has been limited by failed efforts to maintain such cells in the desirable multi-potent NSC state without continuous expression of the transcription factors used initially to reprogram them.

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Harvard researchers genetically ‘edit’ human blood stem cells

November 7, 2014 by · Leave a Comment 

Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General (MGH) and Boston Children’s hospitals (BCH) for the first time have used a relatively new gene-editing technique to create what could prove to be an effective technique for blocking HIV from invading and destroying patients’ immune systems.

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Scientists generate first human stomach tissue in lab with stem cells

October 30, 2014 by · Leave a Comment 

Scientists used pluripotent stem cells to generate functional, three-dimensional human stomach tissue in a laboratory – creating an unprecedented tool for researching the development and diseases of an organ central to several public health crises, ranging from cancer to diabetes.

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Scientists develop barcoding tool for stem cells

October 6, 2014 by · Leave a Comment 

A 7-year-project to develop a barcoding and tracking system for tissue stem cells has revealed previously unrecognized features of normal blood production: New data from Harvard Stem Cell Institute scientists at Boston Children’s Hospital suggests, surprisingly, that the billions of blood cells that we produce each day are made not by blood stem cells, but rather their less pluripotent descendants, called progenitor cells. The researchers hypothesize that blood comes from stable populations of different long-lived progenitor cells that are responsible for giving rise to specific blood cell types, while blood stem cells likely act as essential reserves.

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Scientists identify rare stem cells that hold potential for infertility treatments

September 6, 2014 by · Leave a Comment 

Rare stem cells in testis that produce a biomarker protein called PAX7 help give rise to new sperm cells — and may hold a key to restoring fertility, research by scientists at UT Southwestern Medical Center suggests.

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