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Stem cell injection may soon reverse vision loss due to age-related macular degeneration

April 16, 2015 by · Leave a Comment 

An injection of stem cells into the eye may soon slow or reverse the effects of early-stage age-related macular degeneration, according to new research from scientists at Cedars-Sinai. Currently, there is no treatment that slows the progression of the disease, which is the leading cause of vision loss in people over 65.

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Scientists sniff out unexpected role for stem cells in the brain

October 14, 2014 by · Leave a Comment 

For decades, scientists thought that neurons in the brain were born only during the early development period and could not be replenished. More recently, however, they discovered cells with the ability to divide and turn into new neurons in specific brain regions. The function of these neuroprogenitor cells remains an intense area of research. Scientists at the National Institutes of Health (NIH) report that newly formed brain cells in the mouse olfactory system — the area that processes smells — play a critical role in maintaining proper connections. The results were published in the October 8 issue of the Journal of Neuroscience.

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Inner ear stem cells hold promise for restoring hearing

June 22, 2014 by · Leave a Comment 

Spiral ganglion cells are essential for hearing and their irreversible degeneration in the inner ear is common in most types of hearing loss. Adult spiral ganglion cells are not able to regenerate. However, new evidence in a mouse model shows that spiral ganglion stem cells present in the inner ear are capable of self-renewal and can be grown and induced to differentiate into mature spiral ganglion cells as well as neurons and glial cells, as described in an article inBioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the BioResearch Open Access website.

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Neurons transplanted into Parkinson’s-affected brains appear healthy after 14 years

June 7, 2014 by · Leave a Comment 

When transplanted into the midbrains of adult patients with Parkinson’s disease, dopamine neurons derived from fetal tissue can remain healthy for many years. The findings reported in the Cell Press journal Cell Reports on June 5th suggest that transplanted neurons don’t degenerate over time as some had suggested and feared they would, which provides further rationale for pursuing stem cells as a source for transplant-ready dopamine neurons, according to the researchers.

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Neuron tells stem cells to grow new neurons

June 2, 2014 by · Leave a Comment 

Duke researchers have found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons. Though the experiments are in their early stages, the finding opens the tantalizing possibility that the brain may be able to repair itself from within.

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CU-Boulder stem cell research may point to new ways of mitigating muscle loss

February 20, 2014 by · Leave a Comment 

New findings on why skeletal muscle stem cells stop dividing and renewing muscle mass during aging points up a unique therapeutic opportunity for managing muscle-wasting conditions in humans, says a new University of Colorado Boulder study.

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Stem cell therapy following meniscus knee surgery may reduce pain, restore meniscus

January 17, 2014 by · 1 Comment 

A single stem cell injection following meniscus knee surgery may provide pain relief and aid in meniscus regrowth, according to a novel study appearing in the January issue of the Journal of Bone and Joint Surgery (JBJS).

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Gene therapy for human skin disease produces long-term benefits

December 29, 2013 by · Leave a Comment 

Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear. In a study online December 26th in the ISSCR’s journal Stem Cell Reports, published by Cell Press, researchers evaluated a patient with a genetic skin disorder known as epidermolysis bullosa (EB) nearly seven years after he had undergone a gene therapy procedure as part of a clinical trial. The study revealed that a small number of skin stem cells transplanted into the patient’s legs were sufficient to restore normal skin function, without causing any adverse side effects.

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Stem Cell based gene therapy for human skin disease produces long-term benefits

December 26, 2013 by · Leave a Comment 

Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear. In a study online December 26th in the ISSCR’s journal Stem Cell Reports, published by Cell Press, researchers evaluated a patient with a genetic skin disorder known as epidermolysis bullosa (EB) nearly seven years after he had undergone a gene therapy procedure as part of a clinical trial. The study revealed that a small number of skin stem cells transplanted into the patient’s legs were sufficient to restore normal skin function, without causing any adverse side effects.

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New hope for stem cells, regenerative medicine emerges from the lab

December 17, 2013 by · Leave a Comment 

JoVE, the Journal of Visualized Experiments, has published a novel technique that could resolve a snag in stem cell research for application in regenerative medicine—a strategy for reprograming cells in vivo to act like stem cells that forgoes the risk of causing tumors.

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