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A snapshot of stem cell expression

October 2, 2015 by · Leave a Comment 

Researchers on the Wellcome Genome Campus reveal new genes involved in stem cell pluripotency, new subpopulations of cells and new methods to find meaning in the data. Published in Cell Stem Cell, the findings have implications for the study of early development.

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New way to repair nerves: Using exosomes to hijack cell-to-cell communication

September 15, 2015 by · Leave a Comment 

Regenerative medicine using stem cells is an increasingly promising approach to treat many types of injury. Transplanted stem cells can differentiate into just about any other kind of cell, including neurons to potentially reconnect a severed spinal cord and repair paralysis.

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Pancreatic cancer stem cells could be ‘suffocated’ by an anti-diabetic drug

September 11, 2015 by · Leave a Comment 

Cancer cells commonly rely on glycolysis, the type of metabolism that does not use oxygen to generate their energy however, researchers from Queen Mary University of London’s Barts Cancer Institute and the Spanish National Cancer Research Centre (CNIO) in Madrid have now found that not all cancer cells are alike when it comes to metabolism.

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Sustained remission of multiple myeloma achieved after personalized cellular therapy

September 10, 2015 by · Leave a Comment 

A multiple myeloma patient whose cancer had stopped responding after nine different treatment regimens experienced a complete remission after receiving an investigational personalized cellular therapy known as CTL019 developed by a team at the University of Pennsylvania. The investigational treatment was combined with chemotherapy and an autologous stem cell transplant – a new strategy designed to target and kill the cells that give rise to myeloma cells.

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Variations in cell programs control cancer and normal stem cells

September 3, 2015 by · Leave a Comment 

In the breast, cancer stem cells and normal stem cells can arise from different cell types but tap into distinct yet related stem cell programs, according to Whitehead Institute researchers. The differences between these stem cell programs may be significant enough to be exploited by future therapeutics.

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Researchers mimic viral infection in colon cancer stem cells

August 27, 2015 by · Leave a Comment 

Researchers targeting colorectal cancer stem cells – the root cause of disease, resistance to treatment and relapse – have discovered a mechanism to mimic a virus and potentially trigger an immune response to fight the cancer like an infection.

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Stem cells help researchers study the effects of pollution on human health

August 10, 2015 by · Leave a Comment 

A recent study published in the Journal of Environmental Sciences (JES) shows that embryonic stem cells could serve as a model to evaluate the physiological effects of environmental pollutants efficiently and cost-effectively.

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NYSCF Global Stem Cell ArrayTM brings precision medicine one step closer to the clinic

August 3, 2015 by · Leave a Comment 

Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute successfully designed a revolutionary, high-throughput, robotic platform that automates and standardizes the process of transforming patient samples into stem cells. This unique platform, the NYSCF Global Stem Cell ArrayTM, for the first time gives researchers the scale to look at diverse populations to better understand the underlying causes of disease and create new individually tailored treatments, enabling precision medicine in patient care.

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Stem cell transplantation for children with rare form of leukemia improves outcomes

July 24, 2015 by · Leave a Comment 

Researchers in the Division of Hematology, Oncology and Blood & Marrow Transplantation at Children’s Hospital Los Angeles have shown greatly improved outcomes in using stem cell transplantation to treat patients with a serious but very rare form of chronic blood cancer called juvenile myelomonocytic leukemia (JMML).

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Stem cells move one step closer to cure for genetic diseases

July 16, 2015 by · Leave a Comment 

Stem cells are key for the continual renewal of tissues in our bodies. As such, manipulating stem cells also holds much promise for biomedicine if their regenerative capacity can be harnessed. However, understanding how stem cells govern normal tissue renewal is a field still in its infancy.

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