Clarifying the effect of stem cell therapy on cancer
April 29, 2013 by admin · Leave a Comment
Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central’s open access journal Stem Cell Research & Therapy. Human mesenchymal stem cells (MSC), isolated from bone marrow, caused changes in blood vessels supplying the tumor, and it is this modification of blood supply which seems to impact tumor growth.
New method developed to expand blood stem cells for bone marrow transplant
March 22, 2013 by admin · Leave a Comment
More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation — a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.
Protein central to cancer stem cell formation provides new potential target
February 13, 2013 by admin · Leave a Comment
Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.
Ovarian cancer stem cell study puts targeted therapies within reach
January 7, 2013 by admin · Leave a Comment
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer’s growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.
Stem cell research provides hope for infertile cancer survivors
December 12, 2012 by admin · Leave a Comment
Radiation and chemotherapy can pack a powerful punch against all kinds of cancers. Those who survive, however, are often left with bad news: Their treatments have rendered them infertile.
Stem cell finding could advance immunotherapy for lung cancer
November 13, 2012 by admin · Leave a Comment
A University of Cincinnati (UC) Cancer Institute lung cancer research team reports that lung cancer stem cells can be isolated—and then grown—in a preclinical model, offering a new avenue for investigating immunotherapy treatment options that specifically target stem cells.
Stem cells show promise for treating infertility in cancer patients
November 1, 2012 by admin · Leave a Comment
A promising stem-cell-based approach for treating infertility has been successfully demonstrated in non-human primates, as reported in a study published by Cell Press in the November issue of the journal Cell Stem Cell. The preclinical study represents an important milestone for translating this strategy to the clinic, particularly for cancer survivors who have been rendered infertile by chemotherapy they received before reaching sexual maturity.
Regulation of telomerase in stem cells and cancer cells
June 28, 2012 by admin · Leave a Comment
Scientists at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg have gained important insights for stem cell research which are also applicable to human tumours and could lead to the development of new treatments. As Rolf Kemler’s research group discovered, a molecular link exists between the telomerase that determines the length of the telomeres and a signalling pathway known as the Wnt/β-signalling pathway.
Exciting New Cancer Treatment Receives Approval For Human Clinical Trials
June 11, 2012 by admin · Leave a Comment
Chances are, you know someone who has been diagnosed with cancer. One out of every three women will contract the disease in their lifetime; for men the odds are even greater. Now, an exciting new protocol has received approval from the FDA and WIRB (Western Institutional Review Board) to conduct a Phase I/II clinical trial on humans for treatment of solid tumor (metastic) cancers using a treatment designed to “supercharge the patient’s immune system and “zap” the cancer cells, destroying them.”
Stanford researcher identifies unusual ‘altruistic’ stem cell behavior with possible link to cancer
June 11, 2012 by admin · Leave a Comment
When most groups of mammalian cells are faced with a shortage of nutrients or oxygen, the phrase “every man for himself” is more apt than “all for one, one for all.” Unlike colonies of bacteria, which often cooperate to thrive as a group, mammalian cells have never been observed to help one another out. But a new study led by a researcher at the Stanford University School of Medicine has shown that certain human embryonic stem cells, in times of stress, produce molecules that not only benefit themselves, but also help nearby cells survive.
